How long does Oxycodone stay in your system?


Oxycodone is an opioid drug used to relieve severe pain in the body. This drug is used to get relief from pain for an extended time. Oxycodone drug has several risks including overdose, drug interactions.

Before consuming oxycodone always know what amount of dosage is needed for your body. Oxycodone stays in your body for 24 hours. After 24 hours drug is completely cleared out of your body. This type of drug is usually prescribed to cancer patients.

Oxycodone drugs are also prescribed in some other cases like surgery, serious injury, and Trauma.

Immediate-Releasing oxycodone are –
1. OxyIR.
2. Roxycodone.
3. Oxaydo.
4. Roxy band.

Extended or controlled oxycodone are –
1. Xtampza ER.
2. Oxycontin.

Some combined medication which includes oxycodone are –
1. Oxycodone combined with Ibuprofen.
2. Oxycodone combined with acetaminophen.
3. Oxycodone combined with aspirin.

Oxycodone drug is extracted from a poppy plant. Mu opioid receptor is bind by the drug which blocks the sensation of feeling (Pain).

Oxycodone drug is a federal control substance. It has high chances of addiction and abuse. If you are taking oxycodone, you may be curious to know how long does oxycodone stay in your system and some other questions. If you stop taking oxycodone it might have a bad effect on you. Oxycodone has several withdrawal symptoms also.


How long does Oxycodone stay in your system?

Measuring half-life of the drug is the actual way to find how long does oxycodone stay in your system. Half-life means the amount of time taken to eliminate half of the drug from the body.

Average half-life cycle of Oxycodone is 3.2 hours. This means that 3.2 hours are needed to clear out drug from the body. Extended doses of oxycodone have half-life cycle of 4 hours to 5.5 hours.

In some cases, the drug is cleared from blood within 22 hours.

Oxycodone still can be detected in Saliva, Hair, Urine longer than that.

1. In Saliva (1-4days).
2. In Urine (3-5days).
3. In Hair (>30 days).


Factors influencing how long does oxycodone will stay in your system

Several factors influence the time taken by the body to eliminate drugs from the system. Some factors are discussed below-

Age –

It takes time for elderly people (above 65) to eliminate oxycodone from their system. Blood conc. in elderly people found to be is 15 times higher than adult ones.

Liver function-

A person suffering from liver dysfunction increases the half-life cycle of oxycodone by 2.5 hours. It means that it will take a longer time to eliminate the drug from your system.

Kidney Function-

A person suffering from kidney problem has increased in 2 hours of half-life cycle of oxycodone.

Alcohol –

Effects of oxycodone drug are increased with alcohol. It can lead to a potentially fatal overdose if you take alcohol and drug combined. It will also take a longer time to clear out from your body.


When to get tested for oxycodone test?

1. When you are getting overdose symptoms of oxycodone i.e. Drug intoxication.

2. If you are taking overdose for a long time as prescribed by the doctor.

3. If you are getting a job somewhere in the governmental workplace and you need documents for specification such as insurance policy, drug test certificates.


What samples are required for oxycodone drug test?

1. A blood sample is taken by inserting a needle into a vein in the arm.

2. A urine sample is also obtained which is must need a sample for any kind of drug test.

3. An absorbent pad is used to collect the saliva sample from gums.

4. Sweat sample is taken from underarms using a patch.

5. The hair sample is collected from hair (Crown) as well as from other areas such as Underarms.


How does oxycodone work?

Oxycodone drugs are taken in various forms from tablets, liquid solution, capsules. This drug has several other names such as Percocet, Tylox, Roxicodone,  Endocet etc. Oxycodone is a pain reliever drug.

Some normal doses of oxycodone are taken every six-seven hours while extended doses are taken every 12 hours. The body takes at least half an hour for initial absorption of oxycodone.

The main reason oxycodone acts as a pain relieving due to its effect on the central nervous system. When we consume oxycodone it binds with opioid receptors.

That’s why your brain doesn’t correspond to any pain. Oxycodone drug depresses the central nervous system including Heart rate, Breathing and other vital functions of the body.

Oxycodone helps in releasing of dopamine chemical. It also triggers an emotional response which helps in relieving pain.


How long it takes to feel the effect of Oxycodone?

It takes at least 30-40 minutes to feel the effect of oxycodone in your system. It usually depends on your dose. Oxycodone comes in form of a tablet, capsule,  liquid solution is taken orally (via the mouth).

This drug must be taken with food. After the initial absorption of a drug, it reaches peak conc. in the bloodstream in 1-2 hours.
Don’t consume extended doses of oxycodone without consulting a doctor. Over the time your body builds up a tolerance to the drug and you may not feel relief in pain.

This means that you need to take extended doses of Oxycodone.


Side-Effects of Oxycodone overdose

Before taking oxycodone you must know the danger of overdoses and drug interactions with alcohol.

If you take a larger dose of a drug which is more than that to relieve the pain it may cause dangerous symptoms in your system. Consuming the recommended amount of Oxycodone still has side-effects like Constipation, Nausea, Drowsiness.

Overdose side-effects of Oxycodone drugs are –
1. Vomiting.
2. Pinpoint pupils.
3. Nausea.
4. Increase in Heart rate.
5. Constipation.
6. Intestinal Tract.
7. Coma.
8. Seizures.
9. Drowsiness.
10. Weak pulse.


Withdrawal symptoms of Oxycodone drugs –

If you stop taking drug suddenly you will get serious withdrawal symptoms. When a body becomes dependent on a drug it may cause withdrawal symptoms. Addiction is different than Dependence. Some withdrawal symptoms which you might experience are –

1. Watery eyes.
2. Muscle cramps.
3. Inability to sleep.
4. Sweating.
5. Vomiting.
6. The problem with Breathing.
7. Joint Aches.

Usually, doctors lower the drug dose from time to time to prevent withdrawal symptoms.

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